Item Type | Name |
Concept
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Islets of Langerhans Transplantation
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Academic Article
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Human, rodent, and canine pancreatic beta-cells express a sodium channel alpha 1-subunit related to a fetal brain isoform.
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Academic Article
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K+ channels: generating excitement in pancreatic beta-cells.
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Academic Article
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NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
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Academic Article
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Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling.
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Academic Article
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Baculovirus-mediated gene transfer into pancreatic islet cells.
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Academic Article
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism.
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Academic Article
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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice.
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Academic Article
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Beta-cell ion channels: keys to endodermal excitability.
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Academic Article
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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.
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Academic Article
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Insulin secretory deficiency and glucose intolerance in Rab3A null mice.
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Academic Article
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TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells.
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Academic Article
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Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores.
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Academic Article
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Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?
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Academic Article
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Visualizing superoxide production in normal and diabetic rat islets of Langerhans.
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Academic Article
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Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.
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Academic Article
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Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration.
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Academic Article
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Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells.
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Academic Article
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Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses.
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Academic Article
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Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion.
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Academic Article
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Islet isolation under cGMP conditions: replacing the coil.
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Academic Article
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Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression.
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Academic Article
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Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
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Academic Article
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Functional MR microimaging of pancreatic beta-cell activation.
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Academic Article
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Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier.
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Academic Article
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Action potentials and insulin secretion: new insights into the role of Kv channels.
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Academic Article
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Delayed rectifier K+ channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness.
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Academic Article
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A nanoporous, transparent microcontainer for encapsulated islet therapy.
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Academic Article
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Glucose sensing in the pancreatic beta cell: a computational systems analysis.
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Academic Article
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Pas de deux or more: the sulfonylurea receptor and K+ channels.
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Academic Article
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Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans.
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Academic Article
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Dependence on NADH produced during glycolysis for beta-cell glucose signaling.
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Academic Article
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The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution.
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Academic Article
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Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.
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Academic Article
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Characterization of a Ca2+ release-activated nonselective cation current regulating membrane potential and [Ca2+]i oscillations in transgenically derived beta-cells.
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Academic Article
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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.
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Academic Article
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Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.
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Academic Article
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FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets.
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Academic Article
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Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells.
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Academic Article
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5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
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Academic Article
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Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling.
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Academic Article
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Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate.
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Academic Article
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Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
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Academic Article
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Metastatic Insulinoma Following Resection of Nonsecreting Pancreatic Islet Cell Tumor: A Case Report and Review of the Literature.
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Academic Article
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TCF1 links GIPR signaling to the control of beta cell function and survival.
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Academic Article
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Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis.
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Academic Article
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The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions.
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Academic Article
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Outcomes of Pancreatic Islet Allotransplantation Using the Edmonton Protocol at the University of Chicago.
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Academic Article
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External Validation of the Newly Developed BETA-2 Scoring System for Pancreatic Islet Graft Function Assessment.
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Academic Article
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Comparative evaluation of simple indices using a single fasting blood sample to estimate beta cell function after islet transplantation.
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Academic Article
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Pain Control, Glucose Control, and Quality of Life in Patients With Chronic Pancreatitis After Total Pancreatectomy With Islet Autotransplantation: A Preliminary Report.
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Academic Article
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Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas.
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Academic Article
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The demise of islet allotransplantation in the United States: A call for an urgent regulatory update.
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Academic Article
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Post-Hoc Analysis of a Randomized, Double Blind, Prospective Study at the University of Chicago: Additional Standardizations of Trial Protocol are Needed to Evaluate the Effect of a CXCR1/2 Inhibitor in Islet Allotransplantation.
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Academic Article
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Islets Transplantation at a Crossroads - Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the American Diabetes Association Congress.
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Grant
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IMAGING BETA CELL FUNCTION WITH BIOSENSORS
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